Both Michael Keaton and Eddie Redmayne walked away winners at the Golden Globes. It was Hungary's first time to win the award.
Picking up two Globes should also help the 20th Century Fox-distributed sci-fi hit "The Martian", which won for motion picture comedy and an acting honor for Matt Damon.
"Carol" went into the night with five nominations but came out empty-handed, as did "The Big Short", about the financial crisis, and admired Catholic Church sex abuse probe film "Spotlight".
Gervais poked fun at Olympic decathlon champion turned Hollywood celebrity Caitlyn Jenner, a pioneer for transgender rights by speaking publicly about her gender change but who was also involved in a deadly vehicle crash past year. And rising star Brie Larson beat veteran Cate Blanchett to win Best Drama Actress for her performance in "Room".
The Golden Globes are selected by the Hollywood Foreign Press Association.
The veteran actor is still Oscar-less after winning the Golden Globe for best actor for his role in the The Revenant, and several publications are predicting this is the role that'll finally earn him an Oscar as well.
"I can not say how surprised I am and how proud I am to have survived this movie", Inarritu said, referring to the harsh conditions in which the movie was filmed. Golden Globes this year was hosted by Ricky Gervais who has previously hosted the event in the past. Oscar nominees will be announced on January 15.
Best foreign language film went to Hungary's Laszlo Nemes' "Son of Saul", a harrowing view of life inside Auschwitz, and best animated film went to Pixar's acclaimed "Inside Out".
The 73rd Golden Globe Awards featured an impressive number of nominations for programs distributed by streaming video on-demand (SVOD) platforms, but in the end, only a few of those programs took home any hardware. The thing about Mozart in the Jungle is that it is the most conservative series in the comedy category. However, Malek's co-star, Christian Slater, managed to take home the award for Best Television Series Supporting Actor for his role in "Mr. Robot". Other films that vied for the Best Drama prize - and should figure in the Oscars conversation - were 1950s-based Carol, harrowing kidnap tale Room, and the summer action blockbuster Mad Max: Fury Road.
After leaving the stage, the host quickly returned holding a beer in his hand - to which Gibson remarked: "You don't need to leave your drink here, I'll put you to sleep another way".