After an FA Cup hat-trick against Fulham, Kane repeated the feat when Stoke City visited White Hart Lane, capping a goal-laden month for the England worldwide.
Mauricio Pochettino: "We are very focused because the game will be very tough".
Heung-min Son scored a hat-trick at White Hart Lane as Mauricio Pochettino's side booked their place at Wembley at the expense of their London rivals, despite losing the services of Harry Kane early on.
To find out how to watch a live stream of the FA Cup quarterfinal match pitting Millwall against Tottenham Hotspur, see the streaming information at the bottom of this article.
The thug approaches the two men singing before punching one of them in the face, with enough force to knock the man to the ground.
Flares were set off ahead of the London derby, and Spurs even had to remove club branded hoardings in the away end - Arsenal supporters had torn them down last season and the club did not want a repeat. He had an opportunity today and scored.
Granted, he may not have the vision or hold-up play that Kane gives Tottenham, but his work-rate and eye for a goal makes him a more than able deputy.
Trippier, once again was heavily involved, and he slipped in Eriksen with a cute pass before the Danish midfielder found Alli at the back post with a low cross, who smashed the ball high into the net to score his 16th goal of the season. "Sometimes the manager is criticised when you rotate the team but look what has happened now". In the key period for any team, we may miss our main striker.
Kane was slow to rise and shook his head before limping off down the tunnel to be replaced by Christian Eriksen. But let's be positive and try and help him. With different names and different players. Liverpool is a point behind Tottenham and Manchester City and 11 adrift of leader Chelsea, having played a game more than the top three. One of our best performances was against Manchester City here, and he was the striker when Harry was injured.
"We have different possibilities and different formations".
On Kane's injury, Alli told BBC One: "It is always terrible to lose a player like Harry, he's been in top form, but I think that shows our depth in quality and everyone stepped up a gear".
Lamela recently travelled to Rome for specialist treatment on his hip but Pochettino said he was still unable to put a date on the player's return to action.
Dan is ESPN FC's Tottenham correspondent.